How do you bring something new to a game that has been built up over the ages? You could add a new storyline, improve graphics etc. Or, you could simply go back to the 16-bit games, and change the fighters to famous scientists. We’re talking about Street Fighters of course. Superinteressante magazine, has come up with a game called Science Combat, which replaces Ryu, Ken and gang with scientists, including Stephen Hawking, Darwin, Einstein, Newton, Tesla, Pythagorus and Madam Curie. Oh, by the way, the final boss, against the scientists is Divinity, or religion if you will. But you don’t want to hear us yapp about that, check out the GIFs below!
Science Combat is 16-bit Street Fighter, but with scientists
It's Science against religion in this one, with Ganesha presenting powers similar to Dhalsim it would seem.